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The classical theories of evolution (mutation accumulation, antagonistic pleiotropy, and disposable soma) [1][2][3] suggest that environmental factors, such as predation, accidents, disease, and/or starvation, ensure that most organisms living in natural settings will not live until old age, and so there will be very little pressure to conserve ...
Instead, they argued, aging evolves because natural selection becomes inefficient at maintaining function (and fitness) at old age. Their ideas were later mathematically...
Only a few broad, overarching theories attempt to explain why we and nearly all living organisms age. These theories compete with each other, making it unlikely that more than one of them could be true. Over time, some theories have fallen out of favor as others have become more widely accepted.
18 Ιουλ 2018 · A classic prediction of the evolutionary theory of aging, due to Medawar and Williams , is that low ‘extrinsic’ (i.e., environmentally imposed) adult mortality leads to the evolution of low intrinsic adult mortality (i.e., slowed aging), while the opposite is expected under high extrinsic adult mortality.
Evolutionary theory predicts that increased lifespan will evolve in the context of low extrinsic mortality, i.e. few environmental threats posing a risk of death. In contrast, short lifespans will evolve in organisms with high extrinsic mortality (for example due to predation).
9 Νοε 2000 · An early explanation for evolution of ageing was the idea that senescence is programmed in order to limit population size or accelerate the turnover of generations, thereby aiding the adaptation...
The evolutionary theory of aging has set the foundations for a comprehensive understanding of aging. The biology of aging has listed and described the “hallmarks of aging,” i.e., cellular and molecular mechanisms involved in human aging.
