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2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a polychlorinated dibenzo -p- dioxin (sometimes shortened, though inaccurately, to simply 'dioxin') [3] with the chemical formula C 12 H 4 Cl 4 O 2. Pure TCDD is a colorless solid with no distinguishable odor at room temperature.
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2,3,7,8-tetrachlorodibenzodioxin (TCDD) is the most toxic of the family of 210 compounds. Seventeen of these PCDD/F compounds having chlorines in the 2,3,7, and 8 positions are designated for special concern because their shape makes them particularly bioactive.
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a halogenated aromatic hydrocarbon (HAH) and widespread environmental pollutant (Poland and Knutson, 1982). TCDD is lipophilic and has a slow rate of metabolism and excretion; thus, it readily concentrates in the food chain (Safe et al., 1991).
1 Απρ 2023 · Thyroid cancer incidence has been steadily rising since the 1970s and exposure to environmental pollutants, including persistent organic pollutants such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and other dioxins, has emerged as a potential explanation for this increase.