Αποτελέσματα Αναζήτησης
26 Ιαν 2021 · With respect to cancer, several in vitro and in vivo studies point to beneficial effects via the immune system by activating macrophages. Zinc modulates oxidative stress and might help to prevent cancer [7]. In case reports, an improvement of the effects of chemotherapy has been described [8].
In this review, we summarize the recent epidemiological, experimental, and clinical findings of zinc dyshomeostasis in cancer, and outline the potential clinical applications of zinc in cancer prevention, diagnosis, and therapy. Zinc signaling. Two forms of zinc exist in our body: protein-bound and free zinc.
The decrease in zinc is due to the down regulation of the ZIP-family zinc uptake transporter. These cells are as "ZIP-deficient/decreased zinc" malignancies. This provides a target for a chemotherapy that can restore the high zinc levels that will manifest cytotoxic effects in the malignant cells.
The patients treated with zinc were mainly diagnosed with head and neck cancer and underwent chemo-, radio- or concurrent radio-chemotherapy. Interventions included the intake of different amounts of zinc supplements and oral zinc rinses.
27 Ιουλ 2015 · Zinc reduced the viability of A549 cells and increased the apoptotic response in both cell lines in a dose-dependent manner. Zinc also amplified the docetaxel effects and reduced its inhibitory concentration 50 (IC 50) values. The superoxide dismutase levels increased in all treatment groups; however, glutathione peroxidase was slightly ...
zinc were mainly diagnosed with head and neck cancer and underwent chemo-, radio- or concurrent radio-chemotherapy. Interventions included the intake of dierent amounts of zinc supplements and oral zinc rinses.
1 Ιουλ 2022 · In the past, zinc supplementation(Zinc gluconate, Zinc sulfate or Glycyrrhizic acid zinc) three times daily (25 mg) during radiotherapy in patients with head and neck cancer significantly increased serum zinc concentrations, and reduced zinc levels resulted in less mucositis and taste disorders than placebo [39]. However, a number of recent ...
