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If a child’s alkaline phosphatase (ALP) level is slightly above the normal range, does it indicate rickets? If the ALP level was found to be below 300 in yesterday’s test, what should be done? How was the past treatment?
4 Νοε 2021 · ALP levels are typically elevated during childhood and puberty due to bone growth and development. Between the ages of 15 to 50 years, ALP levels are slightly higher in males than females. ALP levels then rise again in old age.
ALP is a marker for osteoblastic activity, and growing children have higher ALP levels (7-9). Even in some children, the ALP concentration may be 5 to 10 times than the adult reference interval. The highest ALP levels are detected during the developmental phase of childhood and adolescence (3, 9).
7 Δεκ 2023 · Transient hyperphosphatasemia (TH) of infancy and early childhood is characterized by a marked elevation of serum alkaline phosphatase in the absence of detectable liver or bone disease, with a return to normal levels within weeks or months.
3 Αυγ 2024 · The normal range of values of ALP differs by age and pregnancy status. ALP values are higher in children because their bones are actively growing, while the ALP values increase during pregnancy in tandem with the development of the placenta and the approach of childbirth.
26 Φεβ 2024 · Abnormal ALP levels can indicate an underlying health problem. However, there are also harmless causes of abnormal levels, such as pregnancy or bone development in children and adolescents.
for children with low ALP will facilitate early detection of cases of hypophosphatasia, which, with the availability of enzyme replacement for hypophosphatasia, can be life-saving or avoid years of undiagnosed morbidity.
