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17 Ιουν 2021 · Hyperthermia is a type of treatment in which body tissue is heated to as high as 113 °F to help damage and kill cancer cells with little or no harm to normal tissue. Hyperthermia to treat cancer is also called thermal therapy, thermal ablation , or thermotherapy .
The therapeutic application of heat is very effective in cancer treatment. Both hyperthermia, i.e. heating to 39–45°C to induce sensitization to radiotherapy and chemotherapy, and thermal ablation, where temperatures beyond 50°C destroy tumor cells directly are frequently applied in the clinic.
Because of these effects, heat treatment or thermal therapy is potentially potent against cancer. The effects of heat on cancer cells are well-known. 2 Cell death from exposure to heat is a function of both the intensity of the applied heat and the time of exposure.
High body temperatures are often caused by illnesses, such as fever or heat stroke. But hyperthermia can also refer to heat treatment – the carefully controlled use of heat for medical purposes. Here, we will focus on how heat is used to treat cancer.
24 Ιουν 2020 · The therapeutic application of heat is very effective in cancer treatment. Both hyperthermia, i.e., heating to 39–45 °C to induce sensitization to radiotherapy and chemotherapy, and thermal ablation, where temperatures beyond 50 °C destroy tumor cells directly are frequently applied in the clinic.
Key literature describing modulations to vasculature, cell viability, DNA damage and repair, metabolism, immune system, and tumor metastasis in response to heat will be reviewed along with considerations for its optimal implementation in the clinic to enhance the efficacy of conventional treatments.
The ability to isolate and administer an Hsp-peptide complex from patient tumors, as demonstrated by this study, offers the hope of individualized therapeutic treatment for cancer patients based upon promising preclinical data.
