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  1. 14 Δεκ 2023 · In a study of lab-engineered cells, Harvard Med researchers identify how the immune system neutralizes the herpesvirus. The research maps, for the first time, the maneuvers used by virus and host in the cell nucleus, a poorly understood terrain of host-pathogen interaction.

  2. 17 Νοε 2015 · The obstacles to creating an effective vaccine that protects someone from contracting herpes involve both the virus itself and the tissue where it typically enters the body. Most vaccines generate antibodies – the body’s natural defenses that attack invading microorganisms that can cause disease.

  3. 29 Ιουλ 2016 · These trials demonstrate that substantial protection against HSV disease and herpes zoster can be induced by recombinant viral proteins combined with an adjuvant that induces the appropriate adaptive (T and B cell) immune response, by targeting innate immune antigen-presenting cells.

  4. 15 Ιουλ 2024 · TREATMENT OF HSV-1 INFECTION. General principles — The management of HSV-1 infection in the immunocompetent host depends upon a variety of considerations, including: Whether the patient has primary HSV-1 infection or reactivation disease. The severity of symptoms.

  5. The primary infection is resolved following the induction of the innate immune response that controls replication of the virus until the adaptive immune response can clear the active infection.

  6. The first line of protection against microbes is innate immunity, which encompasses all the mechanisms that provide barriers or restriction to infection and the signaling pathways that produce antiviral molecules.

  7. 8 Ιουλ 2022 · Genital herpes infections are associated with morbidity, transmission to the neonate, and enhanced transmission of human immunodeficiency virus-1 (HIV-1) [1–3]. Development of effective strategies to interrupt transmission and decrease prevalence in adults will require an understanding of disease transmission and natural history, as well as ...

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