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  1. 13 Ιουλ 2023 · For newer keloids, the first treatment option might be compression dressings made from stretchy fabric or other materials. This method is also used after surgery to remove keloids. The goal is to reduce or prevent a scar by putting pressure on the wound as it heals.

  2. Keloids can arise months to years after an injury. The pathogenesis is hypothesised to involve dysregulation of the normal healing process resulting in excessive production of collagen, elastin, proteoglycans, and extracellular matrix proteins. There is an increase in the number of fibroblasts and mast cells.

  3. 17 Ιουλ 2023 · Keloids are a result of aberrant wound healing. Standard wound healing consists of three phases: (1) inflammatory, (2) fibroblastic, and (3) maturation. In keloids, the fibroblastic phase continues, unchecked, resulting in the clinical and histopathological findings.

  4. The aim of targeted therapy is to intervene in the abnormal skin healing process, reduce keloid tissue formation, and promote normal tissue repair. In recent years, many researchers have focused on exploring the molecular mechanisms of keloid tissue nodules and have identified potential targets.

  5. 20 Μαΐ 2020 · Introduction. Scar is a cutaneous development in the skin, culminated by biological wound healing processes. The skin restores the lost tissues by scarring where the new cell population resides in a newly constructed connective tissue with a new vasculature.

  6. 28 Δεκ 2023 · Keloid is a prevalent skin disorder characterized by the abnormal growth of keloid tissue, which usually occurs following wound healing or surgical incisions. It typically progresses through several stages: the inflammatory stage, the proliferative stage, collagen remodeling, and ultimately the formation of keloid.

  7. 1 Μαΐ 2024 · Prevention – Key factors to prevent keloids and hypertrophic scars include promoting rapid wound healing by keeping the wound clean and moisturized, fixing the wound with paper tape to reduce tension, and reducing inflammation at an early stage during the wound healing process. For surgical wounds, it is important that surgical incision be ...

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