Αποτελέσματα Αναζήτησης
30 Απρ 2024 · Pathophysiology. In COPD, the airflow limitation is both progressive and associated with an abnormal inflammatory response of the lungs to noxious gases or particles. Image source: pathophys.org. An inflammatory response occurs throughout the proximal and peripheral airways, lung parenchyma, and pulmonary vasculature.
12 Φεβ 2021 · We discuss the pathophysiology of COPD; describe COPD risk factors, signs, and symptoms that may facilitate earlier diagnosis of COPD; and reinforce the importance of spirometry use in establishing the diagnosis of COPD.
23 Μαρ 2020 · Chronic obstructive pulmonary disease is a common respiratory condition involving progressive lung damage. This article, the first in a two-part series, describes its pathophysiology, diagnosis and prognosis.
7 Αυγ 2023 · Pathophysiology. COPD is an inflammatory condition involving the airways, lung parenchyma, and pulmonary vasculature. The process is thought to involve oxidative stress and protease-antiprotease imbalances.
This article provides an overview of the pathophysiology of chronic obstructive pulmonary disease including the physiological mechanisms that are known precursors. The roles of environmental and genetic causes are considered. α 1-Antitrypsin deficiency is also discussed as it relates to the development of airflow obstruction.
26 Σεπ 2021 · Oxidative stress is the primary cause of COPD pathogenesis, triggering apoptosis, extracellular matrix remodeling, inactivation of protease inhibitors, mucus secretion, NF-κB activation, mitogen-activated protein kinase (MAPK) activation, chromatin remodeling, and pro-inflammatory gene transcription [71,74,75].
This article provides an overview of the pathophysiology of chronic obstructive pulmonary disease including the physiological mechanisms that are known precursors.
