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During the past two decades many reports dealt with the possible effects of cigarette smoking on thyroid hormone synthesis, thyroid gland size and thyroid autoimmunity including infiltrative ophtalmopathy of Graves' disease. In this mini-review, issues regarding thiocyanate overload and thyroid disease will be summarized.
- Effects of the Environment, Chemicals and Drugs on Thyroid Function
Drugs affect the transport, metabolism, action and excretion...
- Thyroid Antagonists (Perchlorate, Thiocyanate, and Nitrate) and ...
Perchlorate, thiocyanate, and nitrate are sodium/iodide...
- Effects of the Environment, Chemicals and Drugs on Thyroid Function
Thyroid dysfunction induced by perchlorate, nitrate and/or thiocyanate exposure. (A) In a normal condition, the sodium-iodide symporter (NIS) mediates the iodide uptake, the first limiting step for thyroid hormone synthesis.
30 Απρ 2024 · Thyroid dysfunction (TD) and type 2 diabetes mellitus (T2DM) frequently co-occur and have overlapping pathologies, and their risk increases with age. Thyroid dysfunction along with T2DM will worsen macro- and microvascular complications, morbidity, and mortality.
Thiocyanate is a potential thyroid disruptor due to its capacity to inhibit the uptake of iodide by the thyroid. Thiocyanate also interacts with the enzymatic reactions associated with iodide organification and thyroid hormone synthesis.
27 Σεπ 2016 · Drugs affect the transport, metabolism, action and excretion of T4 and its derivatives as well as regulation at all levels of the hypothalamic-pituitary-thyroid axis. Some drugs may induce hypothyroidism or thyrotoxicosis, and if autoimmune mechanisms are involved, the thyroid dysfunction may not resolve with discontinuance of the drug.
7 Ιουλ 2015 · Perchlorate, thiocyanate, and nitrate are sodium/iodide symporter (NIS) inhibitors that block iodide uptake into the thyroid, thus affecting thyroid function. Thyroid dysfunction can adversely affect somatic growth and development in children. To our knowledge, no studies have examined effects of NIS inhibitors on body size measures. Objective:
1 Ιαν 2023 · Urinary perchlorate, nitrate, and thiocyanate were associated with significant changes in thyroid function markers. •.