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In 2018, deep brain stimulation received FDA approval as an adjunctive treatment for people with intractable focal onset epilepsy. As the newest of the neuromodulatory treatment options in the US for epilepsy, the data on pregnant women, specifically for intractable epilepsy treatment, is sparse.
The clinical management of women with epilepsy on antiepileptic drugs (AEDs) during pregnancy presents unique challenges. The goal of treatment is optimal seizure control with minimal in utero fetal exposure to AEDs in an effort to reduce the risk ...
17 Ιαν 2020 · This report from the International League Against Epilepsy Task Force on Women and Pregnancy aims to provide a summary of relevant data on these risks as a basis for expert opinion recommendations for the management of epilepsy in pregnancy.
However, the treatment of epilepsy during pregnancy is a double-edged sword, because many of the antiepileptic drugs (AEDs) that most effectively control seizures are also teratogenic to various degrees, posing another obvious risk to the developing fetus.
5 Μαρ 2024 · This topic will discuss the management of epilepsy during pregnancy, delivery, and the postpartum period. The risks associated with epilepsy and the risks of antiseizure medication (ASM) treatment during pregnancy are discussed separately.
Most women with epilepsy maintain their seizure control during pregnancy. Prepregnancy seizure control is the most important predictor of seizure control during pregnancy. Nonadherence to AED medication and alterations in AED clearance are major causes of break-through seizures. Pregnancy can have a major impact on the pharma-cokinetics of AEDs.
1 Δεκ 2019 · The risks associated with use of antiepileptic drugs during pregnancy are a major concern for all women with epilepsy with childbearing potential. These risks have to be balanced against foetal and maternal risks associated with uncontrolled seizures.
