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10 Νοε 2022 · The first step in the evaluation of a patient with hypercalcemia is to verify with repeat measurement (total calcium corrected for albumin) that there is a true increase in the serum calcium concentration. If available, previous values for serum calcium should also be reviewed.
- Clifford J Rosen, MD
Diagnostic approach to hypercalcemia. Author Elizabeth...
- Clifford J Rosen, MD
7 Μαΐ 2024 · Identify signs and symptoms of hypercalcemia. Interpret laboratory and imaging results accurately to determine the underlying cause of hypercalcemia. Evaluate differentials to determine the etiology of hypercalcemia. Determine appropriate treatment options for hypercalcemia.
2 Ιουν 2015 · Mild hypercalcaemia is usually caused by primary hyperparathyroidism, the treatment for which is typically surgery; those aged 50 or more with serum calcium levels <0.25 mmol/L above the upper limit of normal and without end organ damage may be followed up conservatively.
1 Μαΐ 2003 · The most common causes of hypercalcemia are primary hyperparathyroidism and malignancy. Some other important causes of hypercalcemia are medications and familial hypocalciuric hypercalcemia.
Abnormalities of parathyroid function, bone resorption, renal calcium reabsorption or dihydroxylation of vitamin D may cause regulatory mechanisms to fail and serum calcium to rise. Serum calcium is bound to albumin, and measurements should be adjusted for serum albumin.
17 Απρ 2023 · Hypercalcemia may be caused by: Endocrine Disorders with Excess PTH including primary sporadic and familial hyperparathyroidism (syndromic and non-syndromic), and tertiary hyperparathyroidism; Endocrine Disorders Without Excess PTH including hyperthyroidism, pheochromocytoma, VIPoma, hypoadrenalism, and Jansen's Metaphyseal Chondrodysplasia; Mal...
Here we review normal calcium homeostasis as a basis to discuss the pathogenesis of hypercalcemia, then examine the clinical presentation of hypercalcemia, its diagnostic evaluation, and appropriate treatment options.