Αποτελέσματα Αναζήτησης
1 Νοε 2023 · CD8 T cells play crucial roles in immune surveillance and defense against infections and cancer. After encountering antigenic stimulation, naïve CD8 T cells differentiate and acquire...
- Cytotoxic CD8 + T cells in cancer and cancer immunotherapy - Nature
Cytotoxic T cells expressing cell-surface CD8 are the most...
- T cells in health and disease
T cells are crucial for immune functions to maintain health...
- Cytotoxic CD8 + T cells in cancer and cancer immunotherapy - Nature
15 Σεπ 2020 · Cytotoxic T cells expressing cell-surface CD8 are the most powerful effectors in the anticancer immune response and form the backbone of current successful cancer immunotherapies.
19 Ιουν 2023 · T cells are crucial for immune functions to maintain health and prevent disease. T cell development occurs in a stepwise process in the thymus and mainly generates CD4+ and CD8+ T...
This review summarizes the current understanding of CD8+ T cell function and differentiation in cancer, focusing on key subtypes and states. It discusses the factors that influence CD8+ T cell priming, metabolism, and response to immunotherapy in the tumor microenvironment.
Abstract. CD8 + T cells are end effectors of cancer immunity. Most forms of effective cancer immunotherapy involve CD8 + T cell cytotoxic function. Here we review the current understanding of T cell function in cancer, focusing on key CD8 + T cell subtypes and states. We discuss factors that influence CD8 + T cell differentiation and function in cancer through a framework that incorporates the ...
10 Οκτ 2023 · CD8 + T cells are end effectors of cancer immunity. Most forms of effective cancer immunotherapy involve CD8<sup>+</sup> T cell effector function. Here, we review the current understanding of T cell function in cancer, focusing on key CD8<sup>+</sup> T cell subtypes and states.
1 Νοε 2023 · CD8 T cells play crucial roles in immune surveillance and defense against infections and cancer. After encountering antigenic stimulation, naïve CD8 T cells differentiate and acquire effector functions, enabling them to eliminate infected or malignant cells.
