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3 Ιαν 2019 · Glomerular endothelial cells are highly fenestrated and are covered on their luminal surface by a thick glycocalyx, which participates in the sieving properties of the glomerular filtration...
Glomerular endothelial cell (GEnC) fenestrations are analogous to podocyte filtration slits, but their important contribution to the glomerular filtration barrier has not received corresponding attention.
8 Νοε 2021 · In vivo, selective inactivation of PAI-1 in endothelial cells protected glomeruli from lesion development and podocyte loss in aged mice. In vitro, blocking PAI-1 in supernatants from senescent endothelial cells prevented podocyte apoptosis.
19 Φεβ 2024 · Among three kinds of intraglomerular cells including podocytes, glomerular endothelial cells (GECs) and mesangial cells (MCs), the alterations in one cell type can produce changes in the others. The cell-to-cell crosstalk plays a crucial role in maintaining the glomerular filtration barrier (GFB) and homeostasis.
25 Μαρ 2021 · Multiple specialized endothelial cell phenotypes coexist within the renal glomeruli, cortex and medulla; these function to support glomerular filtration, the reabsorption and secretion of ions...
9 Απρ 2021 · The analysis reveals genetic programs for all four glomerular cell types (podocytes, glomerular endothelial cells, MCs and PECs) as well as rare glomerulus-associated macula densa cells.
5 Οκτ 2020 · Glomerular endothelial cell (GEnC) dysfunction is important in the pathogenesis of glomerular sclerotic diseases, including Focal Segmental Glomerulosclerosis (FSGS) and overt diabetic nephropathy (DN). GEnCs form the first cellular barrier in direct contact with cells and factors circulating in the blood.
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σχετικά με: glomerular endothelial cellOrder Canine Glomerular Endothelial Primary Cells at BioVenic. Reliable Cell Provider. Offer a Vast Selection of Animal Cells from Bovine, Porcine, Canine, Feline, Equine, etc.