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1 Δεκ 2021 · An effective and scalable cure strategy is a top priority for the HIV research field; this Review discusses recent advances, knowledge gaps, and priority research areas for the next 5 years.
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21 Ιουν 2023 · HIV cure research has entered an era of proof-of-concept testing, with multiple groups seeking to use immunotherapy to control the virus post-antiretroviral therapy (ART).
Recent years have seen major investments into HIV cure research, seeking a permanent cure or remission. The purpose of this review is to consider how this important research agenda could be broadened to include issues of acceptability and appropriateness for different populations.
30 Νοε 2020 · We propose steps to plan for an HIV cure now, including defining a target product profile and establishing the HIV Cure Africa Acceleration Partnership (HCAAP), a multidisciplinary public-private partnership that will catalyse and promote HIV cure research through diverse stakeholder engagement.
In vivo delivery of gene-editing tools to either target the virus, boost immunity or protect cells from infection, also holds promise for future HIV cure strategies. In this Review, we discuss advances related to HIV cure in the last 5 years, highlight remaining knowledge gaps and identify priority areas for research for the next 5 years.
There are two main considerations driving the desire to cure HIV: to improve long-term health for individuals who are infected with HIV and to reduce on a community level the transmission of the virus to other individuals.
10 Μαρ 2020 · With the need for lifelong treatment of HIV with antiretroviral therapy (ART), and the associated costs, adverse events, and stigma, there is a growing need and a global scientific effort to find a cure, with many interventions being currently assessed in animal models and clinical trials.1 But what does a cure for HIV mean and how can ...
