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Activin and inhibin are two protein complexes that regulate FSH secretion and have opposite effects. Learn about their structure, function, mechanism of action, and clinical significance in this Wikipedia article.
Inhibin is a peptide hormone produced by ovarian and testicular cells that inhibits the release of follicle-stimulating hormone (FSH) from the pituitary gland. FSH is involved in the development and function of sex glands and reproductive cycles.
1 Μαρ 2005 · This article summarizes the recent advances on the role of inhibins in human gametogenesis, conception, implantation and early pregnancy. It covers the structure, receptor, assays and clinical relevance of inhibin A and B in male and female fertility and gynaecological diseases.
1 Οκτ 2014 · Inhibin is a gonadal hormone that regulates pituitary FSH production and ovarian folliculogenesis. This review traces the discovery, molecular cloning, and biological roles of inhibin in various organ systems, as well as its diagnostic value in reproductive and pregnancy-related conditions.
Inhibin is a heterodimeric molecule composed of an and subunit linked by disulphide bonds. As a member of the TGF-β superfamily, inhibin is quite unique; it is the only endocrine hormone in the family, the only one to possess an α-subunit and the only one that acts as an antagonist (Zhu et al., 2010).
1 Μαΐ 2023 · Inhibin (INH) is a glycoprotein hormone that inhibits follicle-stimulating hormone (FSH) synthesis and secretion. This review summarizes the current findings on the structure, function, and mechanism of INH in the reproductive system of animals, as well as the potential applications of INH gene therapy.
Inhibin is best known as a reproductive hormone that inhibits release of follicle-stimulating hormone (FSH) from the pituitary gland. Over the last decade or so a number of other biological roles have emerged, putting inhibin more in the class of a growth factor.
