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10 Μαρ 2020 · The London patient has been in HIV-1 remission for 30 months with no detectable replication-competent virus in blood, CSF, intestinal tissue, or lymphoid tissue. Donor chimerism has been maintained at 99% in peripheral T cells. We propose that these findings represent HIV-1 cure.
- The London patient—5 years on from identifying himself
He had received a stem-cell transplant in 2016 to treat...
- The London patient—5 years on from identifying himself
8 Μαρ 2019 · This week, a second patient, known as the “London Patient,” is reportedly in remission. Here’s what you need to know about HIV and this important scientific breakthrough.
He had received a stem-cell transplant in 2016 to treat stage 4 Hodgkin lymphoma from a donor who was homozygous for the CCR5 Δ32 mutation, which rendered him resistant to HIV infection. The Hodgkin lymphoma, which had almost killed him, went into remission.
24 Μαρ 2022 · The second case, known as the London patient (a man with Hodgkin lymphoma), was reported more recently and has been in HIV remission for more than 30 months after a bone marrow stem cell transplant.
Interpretation: The London patient has been in HIV-1 remission for 30 months with no detectable replication-competent virus in blood, CSF, intestinal tissue, or lymphoid tissue. Donor chimerism has been maintained at 99% in peripheral T cells. We propose that these findings represent HIV-1 cure.
15 Φεβ 2022 · The “London patient” (a Latino male) has been in HIV remission for more than 30 months. This third case of HIV remission suggests that CCRΔ5/Δ32 cord stem cell transplantation should be considered to achieve HIV remission and cure for people living with HIV who require such a transplant for other diseases, according to the study team.
8 Μαρ 2019 · Doctors recently reported a case of the second patient to have achieved HIV remission after undergoing a bone marrow transplant to treat cancer and ending ART. The so-called “London Patient,” who has chosen to remain anonymous, was first diagnosed with HIV in 2003.