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11 Αυγ 2024 · Methylprednisolone is a systemic synthetic corticosteroid that exerts a wide range of physiologic effects similar to naturally occurring glucocorticoids. Methylprednisolone is typically prescribed due to its anti-inflammatory and immunosuppressive activity in the human body.
11 Αυγ 2024 · Methylprednisolone is an FDA-approved medication used for managing and treating various conditions, including allergic reactions, arthritis, asthma exacerbations, long-term asthma maintenance, and acute exacerbations of multiple sclerosis.
17 Απρ 2021 · A 36-year-old woman developed an extended-spectrum B-lactamase-producing Escherichia Coli infection and bacterial abscess during treatment with methylprednisolone for hyperinflammatory syndrome. The woman presented to the emergency department with fever, thoracic pain and cough.
9 Απρ 2021 · This systematic review and meta-analysis demonstrated that Methylprednisolone is safe against ARDS. It may reduce mortality and shorten the time of mechanical ventilation. However, well-designed and large-sample studies were required to fully characterize the efficacy and safety of methylprednisolon …
3 Ιαν 2022 · Methylprednisolone is a glucocorticoid used to suppress the autoimmune and inflammatory responses in rheumatic diseases and was administrated to patients during the earlier severe acute respiratory syndrome (SARS) and the Middle East respiratory syndrome outbreak [5, 6].
5 Σεπ 2015 · We aimed to assess whether oral administration of high-dose methylprednisolone was non-inferior to intravenous administration. Methods: We did this multicentre, double-blind, randomised, controlled, non-inferiority trial at 13 centres for multiple sclerosis in France.
Evidence points to the host’s inability to fully down-regulate systemic inflammation and restore tissue homeostasis as the dominant pathophysiologic processes contributing to acute and chronic adverse outcomes in community-acquired pneumonia (CAP) [9, 10].
