Αποτελέσματα Αναζήτησης
25 Φεβ 2015 · New oral anticoagulants (NOACs) are an alternative for vitamin K antagonists (VKAs) to prevent stroke in patients with non-valvular atrial fibrillation (AF). Unlike VKAs, these anticoagulants do not require routine INR monitoring and possess favorable pharmacological properties.
24 Μαΐ 2023 · Anticoagulation with direct oral anticoagulants (DOACs) reduces the risk of ischemic stroke and systemic embolism among persons with atrial fibrillation. 1 However, whether the timing of...
25 Ιουλ 2022 · Early use of anticoagulants may decrease the volume of infarcted cerebral tissue by reducing the propagation of a thrombus in an intracerebral artery and, therefore, decrease the neurological deficit and risks of disability and death in patients with acute ischemic stroke (AIS).
Κυριότερες Ειδήσεις
28 Νοε 2023 · Since the pivotal RE‐LY (Randomized Evaluation of Long‐Term Anticoagulation Therapy) trial 11 in 2009, the introduction of direct oral anticoagulants (DOACs) has revolutionized stroke prevention in AF, with all DOACs showing superior or noninferior efficacy and safety compared with vitamin K antagonists (VKAs). However, slight discrepancies ...
12 Νοε 2023 · Meta-analysis of these 2 large randomized trials provides high-quality evidence that oral anticoagulation with edoxaban or apixaban reduces the risk of stroke in patients with device-detected atrial fibrillation and increases the risk of major bleeding.
Oral direct inhibitors of thrombin and activated factor Xa are approved as new anticoagulant drugs. In contrast to vitamin K antagonists (VKA) and heparins, the new agents have single targets in the coagulation cascade and more predictable pharmacokinetics, but they lack validated and available antidotes.
22 Οκτ 2021 · Anticoagulants tested were standard unfractionated heparin, low-molecular-weight heparins, heparinoids, oral anticoagulants, and thrombin inhibitors. Over 90% of the evidence is related to effects of anticoagulant therapy initiated within the first 48 hours of onset.
