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  1. 12 Οκτ 2021 · Peptic ulcers are caused by an imbalance between aggressive factors like hydrochloric acid (HCL), pepsin, refluxed bile, leukotrienes (LTs), reactive oxygen species (ROS), and defensive factors...

  2. 5 Ιουν 2023 · Peptic ulcer disease (PUD) is characterized by discontinuation in the inner lining of the gastrointestinal (GI) tract because of gastric acid secretion or pepsin. It extends into the muscularis propria layer of the gastric epithelium. It usually occurs in the stomach and proximal duodenum.

  3. The JSGE revised the third edition of evidence-based clinical practice guidelines for peptic ulcer disease in 2020 and created an English version. The guidelines cover epidemiology, H. pylori eradication, NSAID- and LDA-related ulcers, idiopathic ulcers, remnant gastric ulcers, and perforation and stenosis.

  4. 1 Ιουν 2012 · A peptic ulcer is a sore on the lining of the stomach or duodenum. The two most common types of peptic ulcer are called “gastric ulcers” and “duodenal ulcers”.

  5. Peptic ulcer disease is a source of significant morbidity and mortality worldwide. Sequelae may range from abdominal pain and gastrointestinal bleeding to gastric outlet obstruc-tion and perforation.

  6. The term peptic ulcer refers to acid peptic injury of the digestive tract, resulting in mucosal break reaching the submucosa. Peptic ulcers are usually located in the stomach or proximal duodenum, but they can also be found in the oesophagus or Meckel’s diverticulum.

  7. 29 Ιαν 2022 · Peptic ulcer is a chronic disease affecting up to 10% of the world’s population. The formation of peptic ulcers depends on the presence of gastric juice pH and the decrease in mucosal defences.

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