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In adults, normal phosphate concentration in serum or plasma is 2.5 to 4.5 mg/dL (0.81 to 1.45 mmol/L) . Hypophosphatemia is defined as serum phosphate concentrations lower than the low end of the normal range, whereas a concentration higher than the high end of the range indicates hyperphosphatemia.
The normal serum phosphorus concentration is 3.4 to 4.5 mg/dl (1.12 to 1.45 mmol/L). This fluctuates with age (it is higher in children than adults), dietary intake, and acid–base status. There is a diurnal variation, which reaches its nadir between 8 and 11 a.m.
28 Αυγ 2023 · Phosphate is an essential electrolyte in the human body as it constitutes about 1% of the total body weight. In an adult, the normal serum phosphate level ranges between 2.5 to 4.5 mg/d L.
Except for specialized cells with high ribonucleic acid content, and for nervous tissue with high myelin content, tissue phosphorus occurs at concentrations ranging approximately from 0.25 to 0.65 mmol (7.8 to 20.1 mg)/g protein.
Elevated concentration of 1α,25(OH) 2 D 3, hypercalciuria, and a low concentration of FGF23 help distinguish intrinsic renal defects in phosphate handling from an FGF23-mediated process. Elevated PTH concentrations with concomitant hypercalcemia are diagnostic of primary hyperparathyroidism.
The serum concentration of phosphate should be kept in the normal range. Of note, renal phosphate threshold 80 and serum phosphate concentrations are age dependent—with an upper limit of normal of 2.4 mmol/L in small infants, 2.1 and 1.9 in preschool and school children, and 1.44 to 1.9 mmol/L in adolescents (according to various reference ...
