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6 Μαρ 2024 · Hypophosphatemia can be induced by decreased net intestinal absorption, increased urinary phosphate excretion, or acute movement of extracellular phosphate into cells. This topic will review the evaluation and treatment of patients with hypophosphatemia.
Phosphate Dosing calculator for hospitalized patients. Treatment of hypophosphatemia including available oral agents and IV dosing
The required dose from a Phosphate Polyfusor® is usually given over 12 – 24 hours but can be given over 6 – 12 hours if necessary, according to severity.
1 Απρ 2023 · intravenous phosphate. Indications: Severe hypophosphatemia (<1 mg/dL or <0.32 mM) Symptoms; Lack of enteral access; Malabsorption; Either potassium phosphate or sodium phosphate may be used, depending on the potassium level. Typical dose: Phosphate <1.5 mg/dL (<0.48 mM) ==> Initial dose of 30 mM phosphate infused over 4 hours
Doses for intravenous phosphate vary in the literature and suggested regimens have included weight based dosing regimens of 0.2-0.5mmol/kg/day up to a maximum of 50mmol. WAHT-PHA-011
Because of its rapid elimination through the kidneys, the dose of phosphate must be given in 3 to 5 divided doses. Adults generally require smaller relative doses than children, between 1 and 2 g of phosphate divided into 2 to 4 doses per day.
Phosphorus is an element, and phosphate comprises 1 atom of phosphorus surrounded by 4 oxygen atoms and is an anion present in humans. Hypophosphatemia in adults is characterized by a serum phos-phate concentration of 2.5 mg/dL.
