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How pyruvate from glycolysis is converted to acetyl CoA so it can enter the citric acid cycle. Pyruvate is modified by removal of a carboxyl group followed by oxidation, and then attached to Coenzyme A.
28 Φεβ 2021 · In the presence of oxygen, pyruvate is transformed into an acetyl group attached to a carrier molecule of coenzyme A. The resulting acetyl CoA can enter several pathways, but most often, the acetyl group is delivered to the citric acid cycle for further catabolism.
18 Δεκ 2021 · Describe how pyruvate, the product of glycolysis, is prepared for entry into the citric acid cycle. If oxygen is available, aerobic respiration will go forward. In eukaryotic cells, the pyruvate molecules produced at the end of glycolysis are transported into mitochondria, which are the sites of cellular respiration.
Oxidation of Pyruvate. In eukaryotic cells, the pyruvate molecules produced at the end of glycolysis are transported into the mitochondrial matrix (the middle region of the mitochondria) (Figure \(\PageIndex{1}\)). In the mitochondrial matrix, pyruvate will be transformed into a two-carbon acetyl group by removing a molecule of carbon dioxide.
Pyruvate decarboxylation or pyruvate oxidation, also known as the link reaction (or oxidative decarboxylation of pyruvate[1]), is the conversion of pyruvate into acetyl-CoA by the enzyme complex pyruvate dehydrogenase complex. [2][3] The reaction may be simplified as: Pyruvate + NAD + + CoA → Acetyl-CoA + NADH + CO 2.
How is pyruvate, the product of glycolysis, prepared for entry into the citric acid cycle? What are the products of the citric acid cycle? Connection for AP ® Courses.
