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A clinical pathway for antibiotic selection for patients with severe sepsis and septic shock, based on infection source, immunocompetence, and penicillin allergy. Includes antibiotic options, dosing, and loading doses for different scenarios and organisms.
1 Ιαν 2020 · This article reviews guidance on the diagnosis and management of sepsis and septic shock, with attention to maximizing adherence to best practice statements, and controversies in definitions, diagnostic criteria, and management.
6 Σεπ 2024 · For patients with septic shock associated with likely gram-negative sepsis, we suggest consideration of the use of two antibiotics from different classes to ensure effective treatment of resistant organisms.
The Surviving Sepsis Campaign 2016 Guidelines for Management of Sepsis and Septic Shock recommend prescribing broad-spectrum antibiotic(s) in patients with sepsis, without factoring in the severity of outcome, ie, the consequences of withholding antibiotics if infection turned out to be the cause of the syndrome . It is clear that for some ...
12 Ιουν 2023 · Septic shock is a serious illness, and despite all the advances in medicine, it still carries high mortality, which can exceed 40%. Mortality does depend on many factors, including the type of organism, antibiotic sensitivity, number of organs affected, and patient age.
Sepsis is a common and life-threatening illness in the ICU, requiring timely and effective antimicrobial therapy. The aims of this review are to identify the most common sites of sepsis, the likely pathogens, and the optimal approach to antimicrobial therapy.
26 Αυγ 2021 · A retrospective cohort analysis of bloodstream infection with severe sepsis and septic shock found that the number needed to treat (NNT) with appropriate initial antimicrobial therapy to prevent one patient death was 4.0 (95% CI, 3.7–4.3) .
