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  1. 28 Αυγ 2023 · Anticoagulation is the mainstay of initial treatment for DVT. However, certain patients with extensive acute DVT with a low risk of bleeding can undergo catheter­directed thrombolysis to lyse the intravenous clot.

  2. 2 Οκτ 2020 · The meta-analysis showed that, compared with a shorter course of anticoagulation, treating patients with a longer course of anticoagulation reduced the risk of DVT (RR, 0.50; 95% CI, 0.27-0.95; ARR, 59 fewer per 1000 patients; 95% CI, 86 fewer to 6 fewer; high-certainty evidence).

  3. 4 Δεκ 2020 · The cornerstone of treatment of VTE is anticoagulation. In a majority of patients, therapeutic anticoagulation is effective in preventing thrombus propagation and distal embolization while allowing the endogenous fibrinolytic system to dissolve the existing clots.

  4. 8 Οκτ 2020 · Use of direct oral anticoagulants (DOACs) are recommended as first-line treatment of acute DVT or PE. DOAC therapy is preferred over vitamin K antagonists (VKAs) for most patients without severe renal insufficiency (creatinine clearance <30 ml/min), moderate-severe liver disease, or antiphospholipid antibody syndrome.

  5. Oral-only anticoagulation strategies are now available, using apixaban or rivaroxaban therapy, beginning in the initial treatment phase. In addition, low-dose anticoagulation with either apixaban or rivaroxaban can be used in the secondary prevention phase for appropriate patients.

  6. 29 Απρ 2016 · The direct oral anticoagulants (DOACs) represent a major advance in oral anticoagulant therapy and have replaced the vitamin K antagonists as the preferred treatment for many indications. By simpli...

  7. 27 Ιαν 2020 · Treatment. Anticoagulation should be initiated as soon as the diagnosis of PE is suspected. 8 Unfractionated heparin may be preferred in patients who are candidates for further advanced therapies such as thrombolysis, catheter-directed thrombolytics or embolectomy, or surgical embolectomy because it provides more flexibility for procedures. 4 ...

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