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  1. 16 Ιουν 2023 · Systemic lupus erythematosus (SLE) is a chronic autoimmune disease of unknown cause that can affect virtually any organ of the body. Immunologic abnormalities, especially the production of a number of antinuclear antibodies (ANA), are a prominent feature of the disease.

  2. 8 Αυγ 2024 · Systemic lupus erythematosus (SLE) is a chronic, occasionally life-threatening, multisystem immune-mediated disorder. Patients may present with a wide array of symptoms, signs, and laboratory findings and have a variable prognosis that depends upon the disease severity and type of organ involvement.

  3. www.uptodate.com › contents › table-of-contentsLupus - UpToDate

    Autoantibodies and diagnosis. Antibodies to double-stranded (ds)DNA, Sm, and U1 RNP. Clinical manifestations and diagnosis of systemic lupus erythematosus in adults. Measurement and clinical significance of antinuclear antibodies.

  4. 7 Φεβ 2024 · Systemic lupus erythematosus (also called SLE or just "lupus") is a chronic disease that can affect various parts of the body. Lupus is an autoimmune condition, meaning that your body's immune system (which normally protects the body from infection) attacks your own tissues as though they were foreign.

  5. 7 Μαρ 2024 · Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that can affect any organ, including the nervous system. Estimates of the incidence and prevalence of neurologic and psychiatric symptoms among patients with SLE vary greatly, due in large part to heterogeneity in definitions and methodology.

  6. 9 Ιαν 2024 · Most patients with systemic lupus erythematosus (SLE) will have clinical evidence of kidney disease, usually an abnormal urinalysis, at some point in the course of their disease . Lupus nephritis (LN) typically develops early in the disease course .

  7. www.uptodate.com › contents › antinuclear-antibodies-ana-beyond-the-basicsUpToDate

    18 Ιαν 2024 · Systemic lupus erythematosus — If a diagnosis of SLE is suspected, then additional tests, looking for autoantibodies directed against double-stranded DNA, Sm antigens, and ribosomal P antigens may be ordered. Because these antibodies are relatively specific for SLE, the results may provide important clues to facilitate the diagnosis of SLE ...

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    uptodate lupus nephritis