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σχετικά με: 4-ap multiple sclerosis definitionLearn more about symptoms and treatments for each of the 4 types of MS. One of the most comprehensive multiple sclerosis centers in central Ohio.
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4-Aminopyridine (4-AP) is an organic compound with the chemical formula H2NC5H4N. It is one of the three isomeric aminopyridines. It is used as a research tool in characterizing subtypes of the potassium channel.
2 Μαρ 2021 · As an antagonist of voltage-gated potassium (Kv) channels, 4-aminopyridine (4-AP) is used as symptomatic therapy in several neurologic disorders. The improvement of visual function and motor skills and relieve of fatigue in patients with MS have been attributed to 4-AP.
20 Δεκ 2013 · Animal studies show that 4-AP can improve impulse conduction through demyelinated lesions. In patients with MS this translates into improved walking speed and muscle strength of the lower extremities in a subset of patients at a level that is often of clinical relevance.
1 Σεπ 1991 · In an earlier study, we demonstrated efficacy of single oral doses of 4-aminopyridine (4-AP) in improving motor and visual signs in multiple sclerosis (MS) patients for a mean of 4.97 hours.
The name "multiple sclerosis" is short for multiple cerebro-spinal sclerosis, which refers to the numerous glial scars (or sclerae – essentially plaques or lesions) that develop on the white matter of the brain and spinal cord.
1 Σεπ 2020 · Multiple sclerosis is a chronic autoimmune disease affecting the central nervous system and is characterized by inflammation, demyelination, gliosis, and neuronal loss.
1 Νοε 2024 · Multiple sclerosis is a disease that causes breakdown of the protective covering of nerves. Multiple sclerosis can cause numbness, weakness, trouble walking, vision changes and other symptoms. It's also known as MS.
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σχετικά με: 4-ap multiple sclerosis definitionLearn more about symptoms and treatments for each of the 4 types of MS. One of the most comprehensive multiple sclerosis centers in central Ohio.
