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  1. 1 Μαΐ 2018 · H – Herceptin® (Trastuzumab) Goals of therapy: Dose-Dense AC + TH is often given with the goal of cure and administered either before surgery (neoadjuvant therapy) to shrink the size of the tumor, or after surgery (adjuvant therapy) to kill any cancer cells that may be still present in the body.

  2. 11 Απρ 2024 · AC is a common, effective, combination chemotherapy treatment commonly used to treat early-stage localized breast cancer. AC contains two chemotherapy agents Adriamycin (doxorubicin) and cyclophosphamide which are usually given together or sequentially with weekly paclitaxel (Taxol) or docetaxel (Taxotere), to create a combination called AC-T ...

  3. 8 Οκτ 2014 · Based on these studies, TCH, AC-TH, and sequential anthracycline–trastuzumab are standard adjuvant therapy options in this population. Adjuvant chemotherapy is recommended even for small node-negative HER2-breast cancer, but the threshold for treatment is disputed.

  4. Cost: ~ $530 per cycle "How this cost is calculated" The cost displayed on the protocol is intended as rudimentary guide only for the Australian context. The cost includes anti-cancer drugs only (not antiemetics, supportive medications or consumables), unless otherwise indicated.

  5. 25 Μαΐ 2020 · Abstract. Background: The optimal neoadjuvant treatment for HER2-positive breast cancer is unknown. We wanted to compare the efficacy and safety of the anthracycline regimen EC-TH versus nonanthracycline regimen TCH in neoadjuvant setting for HER2-positive breast cancer.

  6. AC chemotherapy can be used to treat primary breast cancer – breast cancer that hasn’t spread beyond the breast or the lymph nodes under the arm. Sometimes it’s used in combination with other anti-cancer drugs.

  7. 2 Σεπ 2021 · The incremental cost-effectiveness ratio (ICER) of AC-TH versus TCH was $US 52,565 per QALY gained. Conclusions TCH neoadjuvant chemotherapy was feasible and active in HER2-overexpressing breast cancer patients in terms of the pathological complete response, complete response, and partial response rates and manageable toxicities.

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