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  1. AC (Adriamycin® + Cyclo­phospha­mide) followed by THP (Taxol® + Herceptin® + Pertu­zumab) is a Chemotherapy Regimen for Breast Cancer - early stage. How does AC-THP work? Doxorubicin, cyclophosphamide, and paclitaxel are chemotherapy drugs designed to kill or slow the growth of cancer cells.

    • Early Stage

      A disease of either the milk-producing glands known as...

  2. This protocol is part of the AC-TH regimen: 4 cycles of AC, followed by 4 cycles of TH and 13 cycles of trastuzumab. Link to Breast adjuvant AC-TH overview; Link to Breast adjuvant AC (DOXOrubicin and CYCLOPHOSPHamide) three weekly; Drug status: Docetaxel is on the PBS general schedule. Trastuzumab is PBS authority

  3. 14 Δεκ 2023 · Women with early-stage breast cancer that meet criteria for HER2 positivity are treated with chemotherapy and trastuzumab as adjuvant treatment. This topic review will cover the use of adjuvant HER2-directed therapy plus chemotherapy in patients with HER2-positive, early-stage breast cancer (stage I to III).

  4. AC is a combination of two chemotherapy drugs used to treat breast cancer. It takes its name from the initials of these drugs: • doxorubicin (also known as Adriamycin) • cyclophosphamide 2. Who might be offered AC chemot herapy? AC chemotherapy can be used to treat primary breast cancer – breast cancer that hasn’t spread beyond the ...

  5. 2 Απρ 2012 · What is the role of pharmacokinetic and/or phamacogenetic factors when determining optimal chemotherapy dose and delivery (bolus, infusional, therapeutic drug monitoring) for obese patients with cancer?

  6. With pCR as the primary endpoint, the combination of chemotherapy plus dual HER2-targeting agents achieved a pCR rate in breast (ypT0/is) of 45.8%, compared with 29% for trastuzumab and docetaxel, 24% for pertuzumab and docetaxel, and 16.8% for dual HER2 blockade without chemotherapy (P=.0141).

  7. 31 Ιουλ 2017 · Chemotherapy-related toxicities were identified from inpatient and outpatient claims within 6 months of beginning chemotherapy. The full cohort analysis included 1077 women (ACTH: 365; TCH:...

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