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  1. 1 Μαΐ 2018 · Dose-Dense AC is repeated every 2 weeks or 14 days. This is known as one Cycle and is repeated for a total of 4 cycles. During TH treatment, paclitaxel is given every 14 days and trastuzumab is given once a week for the first eight weeks. Then, trastuzumab is given alone every 21 days for 44 weeks.

  2. This treatment regimen consists of two parts: 4 cycles of AC, followed by 4 cycles of TH and 13 cycles of trastuzumab. Breast neoadjuvant/adjuvant AC (DOXOrubicin and CYCLOPHOSPHamide) three weekly. Breast adjuvant TH (DOCEtaxel and trastuzumab) three weekly.

  3. 26 Απρ 2016 · Adjuvant Regimen When an Anthracycline Is Not Preferred. Docetaxel plus cyclophosphamide (TC) × 4 is recommended as an alternative to AC × 4 and offers improved disease-free survival (DFS) and overall survival (OS). Classic CMF with oral cyclophosphamide for six cycles is another option.

  4. 6 Οκτ 2011 · Background. Trastuzumab improves survival in the adjuvant treatment of HER-positive breast cancer, although combined therapy with anthracycline-based regimens has been associated with cardiac...

  5. 17 Ιουν 2017 · For many years, trastuzumab in addition to paclitaxel or docetaxel has been the standard first-line treatment for HER2-positive metastatic breast cancer on the basis of the pivotal trial by Slamon and colleagues, 3 which showed a median overall survival of 25 months.

  6. 13 Σεπ 2019 · The NSABP B-31 compared AC-T regimen, i.e., four cycles of doxorubicin plus cyclophosphamide (AC) followed by four sequential cycles of paclitaxel every 3 weeks with AC-TH regimen, i.e ...

  7. 31 Ιουλ 2017 · The two most commonly used regimens in the United States are ACTH (doxorubicin, cyclophosphamide, paclitaxel, and trastuzumab) and TCH (docetaxel, carboplatin, and...

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