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The American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) requested a brief update of the 2018 recommendations on management of hyperglycemia (1,2), based on the important research findings published in 2019, with a particular focus on new data from large cardiovascular outcomes trials (CVOTs).The authors began work on the brief update in July 2019 ...
16 Ιουλ 2016 · 1) Tight glycemic control reduces complications. 2) Type 2 diabetes is a progressive disease. 3) There remain unmet clinical needs: weight gain, hypoglycemia, etc. 4) Adherence and compliance remain issues. 5) Most therapies fail to adequately control postprandial hyperglycemia.
17 Ιουλ 2013 · If not at target, stage 1: Start with lifestyle and metformin. If A1C ≥7.5% (10) or ≥9% (9, 10), consider short-term combination therapy or insulin, respectively. Stage 2: If A1C is not at target after 3–6 months of metformin therapy, suggest adding incretin therapy (in relation to BMI).
26 Σεπ 2019 · Consensus recommendations for the management of T2DM and CVD through lifestyle management. Type 2 diabetes is related to adverse lifestyle, hence any intervention to improve outcomes in type 2 diabetes should start with therapeutic life style changes.
3 Δεκ 2020 · OBJECTIVE. To compare the long-term efficacy of initiating therapy with metformin/pioglitazone/exenatide in patients with new-onset type 2 diabetes mellitus (T2DM) versus sequential addition of metformin followed by glipizide and insulin. RESEARCH DESIGN AND METHODS.
If after 3 months if A1c is greater than 7% and optimal bedtime dose has been reached with fasting blood glucose at goal, consider adding a pre-meal bolus insulin at the largest meal of the day, pre-meal bolus insulin at each meal or 70/30 premix insulin. DC all oral agents except Metformin.
15 Φεβ 2019 · A concise way to evaluate pharmacotherapy options for type 2 diabetes mellitus is to use the five patient-oriented STEPS criteria: safety, tolerability, efficacy, price, and simplicity.
