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  1. Learning Objectives. Recognize drug-specific and patient factors of antihyperglycemic agents to support patient-provider shared decision making. Demonstrate when and how to intensify therapy Identify opportunities to refer patients to Diabetes Self-Management Education.

  2. Algorithm for the Management of Type 2 Diabetes. STEP 1 – Initial Drug Treatment – Monotherapy: Target HbA1c 48 mmol/mol. Lifestyle advice + Referral to Good2Go Metformin (consider 3 months lifestyle change first) Consider trial of modified-release metformin in patients who experience gastrointestinal side effects with standard release metformin.

  3. This protocol is part of the AC-TH regimen: 4 cycles of AC, followed by 4 cycles of TH and 13 cycles of trastuzumab. Link to Breast adjuvant AC-TH overview; Link to Breast adjuvant AC (DOXOrubicin and CYCLOPHOSPHamide) three weekly; Drug status: Docetaxel is on the PBS general schedule. Trastuzumab is PBS authority

  4. 4 Δεκ 2020 · The target A1C among intensive-control subjects was <6% (42 mmol/mol) in ACCORD, <6.5% (48 mmol/mol) in ADVANCE, and a 1.5% reduction in A1C compared with control subjects in VADT, with achieved A1C of 6.4% vs. 7.5% (46 mmol/mol vs. 58 mmol/mol) in ACCORD, 6.5% vs. 7.3% (48 mmol/mol vs. 56 mmol/mol) in ADVANCE, and 6.9% vs. 8.4% (52 mmol/mol vs ...

  5. Foundational therapy is metformin and comprehensive lifestyle management (including weight management and physical activity) Metformin is the preferred initial glucose lowering medication for most people with T2D. This recommendation is based on the efficacy, safety, tolerability, and extensive clinical.

  6. 1 Ιαν 2009 · Algorithm for the metabolic management of type 2 diabetes; Reinforce lifestyle interventions at every visit and check A1C every 3 months until A1C is < 7% and then at least every 6 months. The interventions should be changed if A1C is > 7%.

  7. How is AC-TH Administered? AC-TH is given through four separate injections into your veins (intravenously). For the first four to six cycles, you will receive AC every two or three weeks. Followed by 12-weekly injections of Paclitaxel and 3-weekly injections of Trastuzumab (given for up to a year). Alternatively,

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