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AC (Adriamycin® + Cyclophosphamide) followed by THP (Taxol® + Herceptin® + Pertuzumab) is a Chemotherapy Regimen for Breast Cancer - early stage. How does AC-THP work? Doxorubicin, cyclophosphamide, and paclitaxel are chemotherapy drugs designed to kill or slow the growth of cancer cells.
- Early Stage
AC (Adriamycin® + Cyclophosphamide) followed by THP...
- Neutropenic Fever
Neutropenia is when you have a low number of infection...
- Early Stage
1. Cycle 2 to 4.
Prophylactic G-CSF may be used to mitigate the risk of haematological toxicities. Patients should have an increased fluid intake of 2-3 litres on day 1 to prevent haemorrhagic cystitis associated with cyclophosphamide. Myalgias and arthralgias may occur with PACLitaxel. Analgesic cover should be considered.
This treatment regimen consists of two parts: 4 cycles of AC, followed by 4 cycles of TH and 13 cycles of trastuzumab. Breast neoadjuvant/adjuvant AC (DOXOrubicin and CYCLOPHOSPHamide) three weekly. Breast adjuvant TH (DOCEtaxel and trastuzumab) three weekly.
11 Απρ 2024 · Sequential Adriamycin-cyclophosphamide therapy with paclitaxel or docetaxel (AC-T) was declared by a 2015 review to likely be the most effective treatment regimen of early-stage breast cancer regardless of hormone status.
7 Δεκ 2022 · The following material represents a subset of chemotherapy and immunotherapy regimens that are used for the treatment of patients with breast cancer, both in the adjuvant and neoadjuvant settings.
14 Δεκ 2023 · Other relevant topics, including principles of testing for HER2 expression on breast cancer tumor tissue, indications for neoadjuvant therapy versus adjuvant therapy in HER2-positive disease, and treatment protocols for HER2-positive disease are discussed elsewhere.
