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  1. A pregnancy test should be considered prior to initiating treatment in females of reproductive potential if sexually active. It is important that all patients of reproductive potential use effective contraception whilst on therapy and after treatment finishes.

  2. AC (Adriamycin® + Cyclo­phospha­mide) followed by THP (Taxol® + Herceptin® + Pertu­zumab) is a Chemotherapy Regimen for Breast Cancer - early stage. How does AC-THP work? Doxorubicin, cyclophosphamide, and paclitaxel are chemotherapy drugs designed to kill or slow the growth of cancer cells.

  3. Treatment overview. This treatment regimen consists of two parts: 4 cycles of AC, followed by 4 cycles of TH and 13 cycles of trastuzumab. Breast neoadjuvant/adjuvant AC (DOXOrubicin and CYCLOPHOSPHamide) three weekly. Breast adjuvant TH (DOCEtaxel and trastuzumab) three weekly.

  4. 8 Οκτ 2014 · Based on these data, TC is considered a standard regimen for adjuvant therapy for node-negative or low-risk node-positive breast cancer. 25 For high-risk breast cancer, good evidence suggests that four cycles of TC is inferior to sequential AC-T (even when concurrent anthracycline is added to TC). 26, 27 Although AC-T has superior breast cancer ...

  5. A pregnancy test should be considered prior to initiating treatment in females of reproductive potential if sexually active. It is important that all patients of reproductive potential use effective contraception whilst on therapy and after treatment finishes.

  6. 26 Απρ 2016 · Adjuvant chemotherapy improves disease-free survival (DFS) and overall survival (OS) independent of age, nodal status, and estrogen receptor (ER) status. However, those with triple-negative and human epidermal growth factor receptor 2 (HER2) –positive breast cancer seem to derive the greatest proportional benefit from systemic chemotherapy ...

  7. A total of 121 women treated with a neoadjuvant pertuzumab-containing regimen or AC-TH for HER2+ invasive breast cancer from 2011 through 2016 were included in the analytical dataset. Baseline patient characteristics overall and by regimen are shown in table 1 .

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