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  1. AC (Adriamycin® + Cyclo­phospha­mide) followed by THP (Taxol® + Herceptin® + Pertu­zumab) is a Chemotherapy Regimen for Breast Cancer - early stage. How does AC-THP work? Doxorubicin, cyclophosphamide, and paclitaxel are chemotherapy drugs designed to kill or slow the growth of cancer cells.

    • Early Stage

      AC (Adriamycin® + Cyclo­phospha­mide) followed by THP...

  2. 14 Δεκ 2023 · Amplification or overexpression of the human epidermal growth factor receptor 2 (HER2) oncogene is present in approximately 15 percent of primary invasive breast cancers [1]. Women with early-stage breast cancer that meet criteria for HER2 positivity are treated with chemotherapy and trastuzumab as adjuvant treatment.

  3. 7 Δεκ 2022 · The following material represents a subset of chemotherapy and immunotherapy regimens that are used for the treatment of patients with breast cancer, both in the adjuvant and neoadjuvant settings.

  4. 8 Οκτ 2014 · Based on these data, TC is considered a standard regimen for adjuvant therapy for node-negative or low-risk node-positive breast cancer. 25 For high-risk breast cancer, good evidence suggests that four cycles of TC is inferior to sequential AC-T (even when concurrent anthracycline is added to TC). 26, 27 Although AC-T has superior breast cancer ...

  5. However, in the United States, doxorubicin/cyclophosphamide (AC) is favored over FEC despite no data comparing neoadjuvant AC-THP with AC-TH or TCHP. Here we report outcomes for patients with localized HER2+ breast cancer treated with pertuzumab-containing neoadjuvant regimens and AC-TH.

  6. 25 Μαΐ 2020 · We wanted to compare the efficacy and safety of the anthracycline regimen EC-TH versus nonanthracycline regimen TCH in neoadjuvant setting for HER2-positive breast cancer.

  7. You must not become pregnant during treatment with AC-T and must use an effective method of contraception. You should take appropriate contraceptive measures during and up to 12 months after cessation of treatment. If pregnancy occurs during your treatment, you must inform your doctor immediately.