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This page looks at the reactions of acid anhydrides with water, alcohols and phenols (including the manufacture of aspirin). These reactions are all considered together because their chemistry is so similar.
Anhydrides react rapidly with water to form two carboxylic acids compounds. Because anhydrides are often prepared from carboxylic acids this reaction serves little synthetic value.
Acid anhydrides are formed from the dehydration reaction of two classes of carboxylic acids, as their name suggests. Anhydrides are highly reactive to nucleophiles and are capable of acylation a variety of proteins and other macromolecules that are important functional groups.
23 Ιαν 2023 · This page looks at the reactions of acid anhydrides with water, alcohols and phenols (including the manufacture of aspirin). These reactions are all considered together because their chemistry is so similar.
31 Οκτ 2019 · It is formed when 1 equivalent of water is removed from two equivalents of an organic acid in a dehydration reaction. In inorganic chemistry it termed as an acidic oxide which reacts with water and form oxyacid or react with a base to form a salt.
A carboxylic acid such as ethanoic acid has the structure: If you took two ethanoic acid molecules and removed a molecule of water between them you would get the acid anhydride, ethanoic anhydride (old name: acetic anhydride).
Acid anhydrides are made from two carboxylic acid groups joined together. To form an acid anhydride, a water molecule is lost in a condensation reaction between two carboxylic acids. This is why acid anhydrides are called anhydride – lack of water.
