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Early, accurate and informed laboratory test results are vital for diagnosis, appropriate treatment, and management. A key challenge for the practitioner, particularly in cases where the illness can present atypically, is distinguishing bacterial tonsillitis infections from early acute IM.
Infectious mononucleosis due to EBV should be suspected in patients, especially teenagers and young adults, who present with an acute illness characterized by sore throat, cervical lymphadenopathy, fever and fatigue.
27 Μαΐ 2010 · At least five randomized, controlled trials of acyclovir treatment for infectious mononucleosis have shown a transient reduction in oropharyngeal viral shedding during treatment, with a...
Infectious mononucleosis is a risk factor for chronic fatigue syndrome. Spontaneous splenic rupture occurs in 0.1 to 0.5% of patients with infectious mononucleosis and is potentially life-threatening. Treatment is mainly supportive. Reduction of activity and bed rest as tolerated are recommended.
The Rational Clinical Examination Systematic Review. Importance Early, accurate diagnosis of infectious mononucleosis can help clinicians target treatment, avoid antibiotics, and provide an accurate prognosis.
Cost-effective, efficient initial laboratory testing for acute infectious mononucleosis includes complete blood count with differential (to assess for greater than 40% lymphocytes and greater than 10% atypical lymphocytes) and a rapid heterophile antibody test.
Infectious mononucleosis, also known as glandular fever, is a viral syndrome characterized by a triad of fever, pharyngitis, and posterior cervical lymphadenopathy. 1 – 3 This article presents...
