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This review details how ADNI studies improved disease progression understanding and clinical trial efficiency. Advances in subject selection, detection of treatment effects, harmonization, and modeling improved clinical trials and plasma biomarkers like phosphorylated tau showed promise for clinical use.
26 Φεβ 2008 · Abstract. The Alzheimer's Disease Neuroimaging Initiative (ADNI) is a longitudinal multisite observational study of healthy elders, mild cognitive impairment (MCI), and Alzheimer's disease.
11 Σεπ 2024 · Although experts at Mayo Clinic review every MRI exam, local reads of all MRI exams are still required to accommodate multisite medicolegal considerations and to ensure that appropriate patient care is provided locally in a timely manner if an emergent finding is seen.
8 Αυγ 2024 · Systematic review: To optimize each imaging sequence for the development of the magnetic resonance imaging (MRI) protocols for phase four of the Alzheimer's Disease Neuroimaging Initiative (ADNI4), the authors used a combination of internal investigation, literature reviews, and expert consensus from site scientists, academic scientists, and ...
This review details how ADNI studies improved disease progression understanding and clinical trial efficiency. Advances in subject selection, detection of treatment effects, harmonization, and modeling improved clinical trials and plasma biomarkers like phosphorylated tau showed promise for clinical use.
11 Σεπ 2024 · The ADNI 4 protocol contains nine different imaging types (e.g., three dimensional [3D] T1-weighted and fluid-attenuated inversion recovery [FLAIR]). Our view is that the ADNI MRI data are a greatly underutilized resource.
The Alzheimer's Disease Neuroimaging Initiative (ADNI) is a longitudinal multisite observational study of healthy elders, mild cognitive impairment (MCI), and Alzheimer's disease.
