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  1. 13 Σεπ 2023 · Adrenal crisis, or Addisonian crisis, is a severe, life-threatening condition characterized by acute adrenal insufficiency. This condition has a substantial mortality rate of 0.5 per 100 patient-years and remains a significant cause of death in individuals with adrenal insufficiency. [1]

  2. Adrenal insufficiency is a common condition with multiple causes that can be divided into primary (adrenal), secondary (pituitary), and tertiary (hypothalamus) forms (figure 1). Each form of adrenal insufficiency has distinctive causes with implications for treatment and follow-up.

  3. 28 Αυγ 2019 · Each year, approximately 6 to 8% of patients with adrenal insufficiency have an incident adrenal crisis. 2,3 Adrenal crises are slightly more frequent in patients with primary...

  4. Adrenal crises are severe manifestations of adrenal insufficiency that result in hospital admission and incur a risk of cardiovascular events, acute renal injury, and death. Evidence from population-based studies indicate that adults older than 60 years have the highest adrenal insufficiency incidence, contribute to the highest number of ...

  5. 11 Οκτ 2024 · These guidelines cover the care of people with primary, secondary, or tertiary adrenal insufficiency (including glucocorticoid-induced adrenal insufficiency) and tailor their recommendations for different patient demographics with specific advice during pregnancy.

  6. Results. AI admissions increased by 62.0%, from 36.78/million to 59.59/million (trend P < .0001). Adrenal crisis (AC) admissions also increased, by 90.1% (from 10.73/million to 20.40/million; trend, P < .00001). These increases were more pronounced in the second decade.

  7. Acute adrenal insufficiency, also termed adrenal crisis, is a life-threatening endocrine emergency brought about by a lack of production of the adrenal hormone cortisol, the major glucocorticoid. Identifying patients at risk and prompt management can save lives.

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