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17 Μαΐ 2023 · Primary adrenal insufficiency — Treatment of adrenal insufficiency requires daily treatment with glucocorticoid and mineralocorticoid pills, usually for life. Androgen replacement may be helpful for some females. The goal of treatment is to stabilize hormone levels and relieve symptoms.
20 Αυγ 2018 · Adrenal insufficiency (AI) is a disorder characterized by the failure of adrenocortical function resulting mainly in impaired secretion of glucocorticoids (GCs) only or of GCs and mineralocorticoids (MCs), hormones crucial for energy, salt and fluid homeostasis.
9 Οκτ 2023 · In addition to hypotension, patients commonly present with nonspecific signs and symptoms including nausea, vomiting, anorexia, fever, fatigue, weakness, and confusion or loss of consciousness. If adrenal crisis is suspected, treatment should be initiated immediately.
3 Φεβ 2024 · In Addison's disease, the adrenal glands make too little cortisol and, often, too little of another hormone, aldosterone. Addison's disease can affect anyone and can be life-threatening. Treatment involves taking hormones to replace those that are missing.
Adrenal insufficiency can arise from a primary adrenal disorder, secondary to adrenocorticotropic hormone deficiency, or by suppression of adrenocorticotropic hormone by exogenous glucocorticoid or opioid medications.
The features of primary adrenal insufficiency (AI) that Thomas Addison eloquently described in 1855 [1] (weakness, fatigue, anorexia, salt craving and orthostatic hypotension) remain important to recognize because treatment may be life saving.
Adrenal failure is an uncommon but life-threatening endocrinopathy with protean manifestations. The diagnosis can often be missed without prompt clinical evaluation and diagnostic work-up and may lead to devastating complications in the form of lethal adrenal crisis.
