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28 Σεπ 2014 · We here showed the genome landscape of a Vero cell line, in which 25,877 putative protein-coding genes were identified in the 2.97-Gb genome sequence. A homozygous ∼9-Mb deletion on chromosome 12 caused the loss of the type I interferon gene cluster and cyclin-dependent kinase inhibitor genes in Vero cells.
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Continuous cell lines that originate from mammalian tissues...
- Chlorocebus Gray, 1870
Although our data set includes samples from most African...
- PubMed
We here showed the genome landscape of a Vero cell line, in...
- Open in a Separate Window
We here showed the genome landscape of a Vero cell line, in which 25,877 putative protein-coding genes were identified in the 2.97-Gb genome sequence. A homozygous ∼9-Mb deletion on chromosome 12 caused the loss of the type I interferon gene cluster and cyclin-dependent kinase inhibitor genes in Vero cells.
The DNA of the African green monkey contains three components that are distinguishable by the kinetics of reassociation. The rapidly reassociating component represents about 20% of the total DNA and is composed almost entirely of a sequence (AGMr(HindIII)-1) which is repeated 6.8 x 10(6) times.
28 Σεπ 2014 · We here showed the genome landscape of a Vero cell line, in which 25,877 putative protein-coding genes were identified in the 2.97-Gb genome sequence. A homozygous ∼9-Mb deletion on chromosome 12 caused the loss of the type I interferon gene cluster and cyclin-dependent kinase inhibitor genes in Vero cells.
A 172-base pair segment of DNA that is repeated several million times in the genome of the African green monkey has been characterized. Sequence analysis revealed that the many repeats of this complex unit are not all identical but represent a set of closely related segments: Sequence divergence occurs at various positions in the segment in a ...
Libraries constructed for paired ends and mate pairs were sequenced with HiSeq2,000 (Illumina Inc., San Diego, California). After quality filtering, sequences were assembled into scaffolds using SGA and SSPACE software27,28 (see Supplementary data for detailed assembly procedure).
Availability of a vervet complete genome sequence will spur a wide range of investigations, including opportunities to develop coordinated projects with genetic and genomic studies of humans and the other sequenced NHPs.
