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27 Μαΐ 2021 · The phase III IMpower150 trial confirmed the superiority of adding atezolizumab to chemotherapy and bevacizumab. 33,34 The improvement in older patients was comparable to younger patients, but the subgroup ≥ 75 years was small (n = 78; 10%) and inconclusive.
23 Μαΐ 2018 · CheckMate 026 evaluated nivolumab compared with platinum-based combination chemotherapy as frontline therapy for patients with advanced NSCLC. 34 Median age of patients enrolled was 64 (range, age 29–89 ); 11% were age 75 years or older. This study did not a priori exclude patients with tumors exceeding a prespecified level of PD-L1 ...
5 Ιαν 2024 · To help you sort out the good from the bad, here are 11 alternative cancer treatments that are generally safe. Plus, there is growing evidence that these treatments may provide some benefit. How can alternative medicine help people with cancer?
For example, in a study of 4,040 patients with colorectal cancer, patients with ≥2 comorbidities had significantly higher odds of not receiving chemotherapy than those with no comorbidities (OR 2.55, 95% CI 1.36–4.78) and patients aged ≥75 years with >1 comorbidity had even greater odds of not receiving chemotherapy compared with younger ...
15 Μαΐ 2019 · According to Professor Matthew Seymour, from the University of Leeds, there are two options – you either risk potentially making a frail and elderly patient sicker by giving them chemo, or you advise against cancer treatment that could give them precious extra time.
2 Σεπ 2020 · Cancer therapy. Oncology. Abstract. Despite substantial improvements in the outcomes of patients with cancer over the past two decades, older adults (aged ≥65 years) with cancer are a rapidly...
14 Μαΐ 2021 · Adjuvant chemotherapy along with one year of trastuzumab is recommended as a standard approach in older patients with no cardiac dysfunction and early-stage, HER2-positive breast cancer ≥0·5 cm (level 2); preferred chemotherapy options include the use of taxanes without anthracyclines, for example in the form of four cycles of docetaxel ...
