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  1. Reference Range. Antinuclear antibody (ANA) tests identify antibodies present in serum that bind to autoantigens present in the nuclei of mammalian cells. Most of these antibodies are IgG, but...

  2. This website can help you decide when to order an ANA, counsel your patient about the test, and interpret ANA test results. When should I order an ANA? ANA testing is one piece of information that may help you diagnose an autoimmune disease like systemic lupus erythematosus.

  3. 13 Ιουν 2021 · The ANA titer is a measure of the amount of ANA in the blood; the higher the titer, the more autoantibodies are present in the sample. Patient samples are often screened for antinuclear antibodies after being diluted 1:40 and 1:160 in a buffered solution.

  4. An ANA test is used to help diagnose autoimmune disorders, including: Systemic lupus erythematosus (SLE). This is the most common type of lupus, a chronic disease affecting multiple parts of the body, including the joints, blood vessels, kidneys, and brain.

  5. The ANA test is a sensitive screening test used to detect autoimmune diseases. Learn how the ANA test procedure is performed and the interpretation of results determined.

  6. 1 Ιαν 2018 · A raised antinuclear factor (ANF) is almost always present in SLE (80-90% - note that uraemia may render the result negative) (1). Other conditions that are associated with a positive ANF but usually of lower titre than in SLE, include: systemic sclerosis (80%) Sjogren's syndrome (60%) polymyositis/dermatomyositis (30%)

  7. The quantitation of an ANA is most commonly reported as a titre, reflecting the final step in a series of two-fold dilutions at which the ANA remains positive (eg. 1:1 280 for a strongly positive ANA, or 1:160 for a weaker, borderline positive ANA).

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