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  1. EFSA’s Scientific Committee has identified possibilities for replacement, reduction and refinement of animal testing within EFSA’s scientific assessment activities. The Committee has also reviewed alternative methodologies that can be used to assess the safety of chemicals and can reduce animal use in toxicological research.

  2. Where a new animal test proves necessary, legislation requires that scientifically-sound approaches to the implementation of the 3Rs – reduction, refinement or replacement of animal use – are used.

  3. Alternatives to animal testing can be used for toxicological research, such as chemical safety and drug effectiveness testing, or other types of biomedical research that examine biological mechanisms of disease.

  4. Due to innovations in science, animal tests are being replaced in areas such as toxicity testing, neuroscience and drug development. But much more needs to be done. Once new non-animal methods have been developed, there are often massive bureaucratic hurdles to implementing and enforcing their use.

  5. 3 Ιουν 2021 · At the JRC’s Ispra site in Italy, the EU Reference Laboratory for alternatives to animal testing (EURL ECVAM) has been developing, validating and promoting scientific methods to replace animal tests for 30 years.

  6. 1 Δεκ 2013 · It aims to highlight the potential areas for alternative approaches in environmental hazard identification and risk assessment. Perspectives and limitations of alternative approaches to animal tests using vertebrates in environmental toxicology, i.e. mainly fish and amphibians, are discussed.

  7. 24 Μαΐ 2011 · Christian Riebeling & Andreas Luch. 82k Accesses. 78 Citations. 11 Altmetric. Explore all metrics. Abstract. On the occasion of the 20th anniversary of the Center for Alternative Methods to Animal Experiments (ZEBET), an international symposium was held at the German Federal Institute for Risk Assessment (BfR) in Berlin.

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