Αποτελέσματα Αναζήτησης
20 Οκτ 2024 · Inhibiting IL-11 signaling reduced the activity of the ERK–AMPK–mTORC1 pathway, leading to reduced cellular senescence and inflammation. Additionally, IL-11 increased the expression of senescence-associated secretory phenotype factors, which exacerbate aging-related conditions.
17 Ιουλ 2024 · Administration of anti-IL-11 to 75-week-old mice for 25 weeks improves metabolism and muscle function, and reduces ageing biomarkers and frailty across sexes.
IL-11 plays a key role in fibrosis across multiple organs and pre-clinical studies have shown that anti-IL-11 treatment has the potential to stop – and even reverse fibrosis – in different fibrotic diseases. Boehringer Ingelheim joined forces with Enleofen, a leader in IL-11 biology, in 2020.
Neutralizing antibodies against IL-11 reduce renal dysfunction and extend life expectancy in some mouse models, thus proposing IL-11 as a therapeutic target for treating chronic kidney disease.
Find the IL-11 antibody that fits your needs. Choose from 1 of 18 IL-11 antibodies, which have been validated in experiments with 11 publications and 29 images featured in our data gallery. Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications.
Mouse anti Human interleukin-11 antibody, clone C16-4B8, recognizes interleukin-11 (IL-11), also known as AGIF. IL-11 belongs to the IL-6 family of cytokines, and plays a protective role in acute inflammatory settings (Traber et al. 2019).
16 Ιουν 2023 · 9MW3811 is a monoclonal antibody designed to target interleukin-11 (IL-11), an immune signaling molecule that’s been implicated in the scar tissue buildup (fibrosis) and inflammation that characterize IPF.
