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  1. 9 Μαΐ 2024 · In this study, we focused on a comparative analysis of the neutralization capacity of vaccine-induced antibodies against four different variants of concern (i.e., Alpha, Beta, Delta, and Omicron) after two and three doses of COVID-19 vaccine.

  2. 6 Αυγ 2024 · Based on two population cohorts in South Africa, we established neutralizing antibodies in serum as correlates of protection against SARS-CoV-2 Delta and Omicron variants for immunity...

  3. 29 Ιουν 2022 · Delta + E484K has an ~8-fold effect on neutralization for primary Delta-infection elicited antibodies, but only a ~3-fold effect for mRNA vaccination- or Delta breakthrough infection-elicited antibodies, comparable to the effect of Delta + K417N mutation.

  4. 27 Μαρ 2024 · To prepare for possible future PDCoV epidemics, we isolated human spike (S)-directed monoclonal antibodies from transgenic mice and found that two of them, designated PD33 and PD41, broadly neutralized a panel of PDCoV variants.

  5. There is a major response to N501Y, including a public IgVH4-39 sequence, with E484K and K417N also targeted. Recognition of these key residues underscores why serum from Beta cases poorly neutralizes early pandemic and Delta viruses.

  6. 16 Απρ 2024 · Our data was limited to anti-SARS-CoV-2 antibodies to clade S and Delta virus, while the XBB variant is circulating worldwide. Our result found that using a new variant as the test virus in MNT assay may reduce NT antibody titers.

  7. 23 Σεπ 2022 · We report that SARS-CoV-2 infection elicits a population immune response that is mediated by a lineage of VH1-69 germline antibodies. A representative antibody R1-32 from this lineage was...

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