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7 Αυγ 2023 · In the study cohort and the sub-cohort with autoimmune disease, ANA + was associated (P ≤ 5 × 10 –5) with 88 and 136 clinical diagnoses respectively, including lupus (OR ≥ 5.4, P ≤ 7.8 × 10 –202) and other autoimmune diseases and complications.
Systemic lupus erythematosus (SLE) is a prototypic autoimmune disease characterized by antinuclear antibodies (ANAs) that form immune complexes that mediate pathogenesis by tissue deposition or cytokine induction.
21 Οκτ 2022 · Antinuclear antibody (ANA) test. A positive test for the presence of these antibodies — produced by your immune system — indicates a stimulated immune system. While most people with lupus have a positive antinuclear antibody (ANA) test, most people with a positive ANA do not have lupus. If you test positive for ANA, your doctor may advise ...
13 Μαρ 2022 · Anti-Nuclear Antibodies Patterns in Patients With Systemic Lupus Erythematosus and Their Correlation With Other Diagnostic Immunological Parameters. Jamil A. Al-Mughales 1,2* 1 Department of Medical Microbiology and Parasitology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.
20 Αυγ 2021 · If your doctor says your ANA test is “positive,” that means you have antinuclear antibodies in your blood — but it doesn’t necessarily mean you have lupus. In fact, a large portion of patients with a positive ANA do not have lupus. Diagnosing lupus is like putting together a puzzle.
16 Ιουν 2023 · Serologic findings are important in suggesting the possibility of SLE, with some antibodies (eg, anti-double-stranded deoxyribonucleic acid [anti-dsDNA] and anti-Smith [anti-Sm]) highly associated with this condition. The clinical manifestations and an approach to the diagnosis of SLE will be reviewed here.
This series of tests, commonly called an ANA panel, checks for the following antibodies: anti-double-stranded DNA, anti-Smith, anti-U1RNP, anti-Ro/SSA, and anti-La/SSB. Some laboratories also include other antibodies in their panel, including antinucleoprotein, anticentromere, or antihistone.
