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4 Νοε 2019 · Fatigue is a common feature of the anti-nuclear antibody (ANA)-positive systemic autoimmune rheumatic diseases (SARDs), including systemic lupus erythematosus (SLE), Sjogren’s disease (SjD), systemic sclerosis (SSc), dermatomyositis, and mixed connective tissue disease [1, 2, 3, 4, 5].
23 Οκτ 2024 · An ANA test is an important initial step in evaluating a potential lupus diagnosis. This test detects antinuclear antibodies in the blood. These antibodies target the body's healthy cells, a hallmark behavior of autoimmune diseases like lupus. A positive ANA test suggests that the immune system is producing these antibodies, which can indicate ...
17 Αυγ 2022 · In most cases, a positive ANA test indicates that your immune system has launched a misdirected attack on your own tissue — in other words, an autoimmune reaction. But some people have positive ANA tests even when they're healthy.
16 Ιουν 2023 · Laboratory testing may reveal leukopenia, anemia, an elevated serum creatinine, hypoalbuminemia, proteinuria, an active urinary sediment, hypocomplementemia, and positive tests for antinuclear antibodies (ANA), including those to double-stranded DNA (dsDNA) and the Smith (Sm) antigen.
22 Ιουλ 2022 · Antinuclear antibody (ANA) autoantibodies, or antibodies produced by the immune system that attack the body’s own cells, are a hallmark of lupus. ANA is usually measured as 0 to 4+ or as a titer (the number of times a blood sample can be diluted and still be positive).
20 Αυγ 2021 · If your doctor says your ANA test is “positive,” that means you have antinuclear antibodies in your blood — but it doesn’t necessarily mean you have lupus. In fact, a large portion of patients with a positive ANA do not have lupus.
The value of detecting a positive ANA in a patient with nonspecific symptoms (such as malaise, fatigue, and generalized pain) is low, particularly if more specific symptoms are absent and other laboratory studies, such as the complete blood cell count, renal function, and urinalysis, are normal.
