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16 Ιουν 2023 · Systemic lupus erythematosus (SLE) is a chronic autoimmune disease of unknown cause that can affect virtually any organ of the body. Immunologic abnormalities, especially the production of a number of antinuclear antibodies (ANA), are a prominent feature of the disease.
The pathognomonic lupus or butterfly rash across the nose occurs in only 30% of patients with SLE. The acute lupus rash may be present elsewhere. Discoid or disc-shaped skin lesions, pathognomonic for discoid lupus, can manifest also in SLE.
Systemic lupus erythematosus (SLE) is a systemic autoimmune disease characterized by flare up phases and others with low disease activity (1). It affects multiple organs such as serous membranes, renal, nervous, and cardiovascular systems, and joints and skin, resulting in multiorgan damage.
4 Αυγ 2023 · Introduction. Systemic lupus erythematosus (SLE) is a systemic autoimmune disease with multisystemic involvement. The condition has several phenotypes, with varying clinical presentations from mild mucocutaneous manifestations to multiorgan and severe central nervous system involvement.
3 Σεπ 2020 · Systemic lupus erythematosus (SLE) is a prototypic autoimmune disease characterized by antinuclear antibodies (ANAs) that form immune complexes that mediate pathogenesis by tissue deposition...
4 ημέρες πριν · Systemic lupus erythematosus (SLE) is a systemic autoimmune disease that can cause inflammation anywhere in the body, including the brain, lungs, and kidneys, in addition to prompting joint and skin problems. Symptoms range from mild to severe, and may periodically improve or worsen; related risk factors include hormone regulation, genes, environmental influences, and certain medications.
Factors leading to SLE include: Genetic predisposition, including haplotype HLA -B8, -DR 3. Exposure to sunlight. Viral infection, particularly Epstein-Barr virus. Hormones. Toxins such as cigarette smoke. Drugs in drug-induced LE. Emotional upset. The manifestations of SLE are due to loss of regulation of the patient's immune system.
