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This review mainly illuminates the current widely used gene therapy drugs, summarizes the viral vectors and non-viral vectors that deliver gene therapy drugs, and sums up the application of gene therapy to treat genetic diseases.
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Genetic diseases seriously threaten human health and have...
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1 Απρ 2022 · Gene therapy serves as an alternative strategy to cure the infection by using chemically modified antisense deoxy oligonucleotides that can inhibit replication and gene expression by targeting different regions in the HSV genome.
1 Απρ 1994 · The most common type of approved clinical trial for cancer gene therapy involves the ex vivo gene transfer of cytokine genes (e.g., tumor necrosis factor, interleukin-2, granulocyte-macrophage colony-stimulating factor) into tumor cells.
Gene therapy has become a clinical reality as market-approved advanced therapy medicinal products for the treatment of distinct monogenetic diseases and B-cell malignancies.
Gene therapy techniques have been aimed at mitigating disease features of recessive and dominant disorders, as well as several cancers and other diseases. While there have been numerous disease...
14 Οκτ 2015 · Gene therapy can be defined as the deliberate transfer of DNA for therapeutic purposes. There is a further implication that only specific sequences containing rel evant genetic information are used; otherwise, transplantation procedures involving bone marrow, kidney or liver could be considered a form of gene therapy.
Introduction. More than 150 years of research and discovery have elapsed between Gregor Mendel’s pea-crossing experiments and the therapeutic use of gene therapies in clinical practice. The hope and promise of curing human diseases have continued to drive the many scienti c and tech- fi.
