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12 Ιουλ 2022 · Aspirin intake in pregnancy is generally safe irrespective of the timing and length of its administration . Although the CPGs included in the present systematic review briefly mentioned the safety profile of aspirin use in pregnancy, most of them did not mention the possible side effects.
Low-dose aspirin (81 mg/day) prophylaxis is recommended in women at high risk of preeclampsia and should be initiated between 12 weeks and 28 weeks of gestation (optimally before 16 weeks) and continued daily until delivery.
13 Ιαν 2023 · The American College of Obstetricians and Gynecologists recommends initiation of 81 mg of aspirin daily for women at risk of preeclampsia between 12 and 28 weeks’ gestation, optimally before 16 weeks, with continuation until delivery.
Conclusion: There is general agreement in the reported indications for aspirin intake in pregnancy, with prior preeclampsia and maternal medical co-morbidity associated with increased risk of preeclampsia being the major indications for aspirin intake.
You should start taking low-dose aspirin between 12 to 16 weeks pregnant, ideally at 12 weeks. Low-dose aspirin started earlier than this is safe and may bring increased benefits but this has not been proven.
The primary USPSTF recommendation remains largely unchanged: prescribe low-dose (81 mg/d) aspirin after 12 weeks of gestation to individuals who are at high risk for preeclampsia (Grade B). However, the USPSTF provided updated guidance regarding moderate-risk factors.
Taking a low dose of aspirin may help to reduce the risk of: • developing hypertension (high blood pressure) and pre-eclampsia (high blood pressure and excessive protein in your urine) • giving birth to your baby prematurely (before 37 weeks) • your baby being smaller than expected.
